Can mice reverse aging?

The 'Benjamin Button' effect: Scientists can reverse aging in mice. The goal is to do the same for humans | CNN These mice are brother and sister, born from the same litter. One has been genetically altered to be old. Now scientists say they have been able to reverse aging as well. The ‘Benjamin Button’ effect: Scientists can reverse aging in mice.

Can gene therapy reverse aging?

Scientists then gave these mice gene therapy to reverse the epigenetic changes, which they said “reset” the mice’s epigenetic program and ultimately reversed the aging the mice had experienced. “We hope these results are seen as a turning point in our ability to control aging,” Sinclair says.

Could a DNA cocktail reverse aging in humans?

Analyses of the mice’s muscles, kidneys, and retinas suggest the cocktail reversed some of the epigenetic changes induced by the DNA breaks. The findings point to a way to drive an animal’s age “forwards and backwards at will,” Sinclair says, and support the idea of epigenome-targeting treatments for aging in humans.

Can epigenetic changes reverse aging?

Scientists demonstrated this via a mouse model where changes in epigenetic information caused mice to first age and then reverse aging. The study appears in the journal Cell. What are epigenetics?